According to the Canadian government, between 10 percent and 35 percent of Canadians 19 and older have a vitamin B12 and C intake below the recommended estimated average requirement (EAR). Additionally, between 10 percent and 35 percent of people from most age and sex groups consume insufficient folate, vitamin B6 and zinc which can result in anemia and various skin conditions. Vitamin B3 is also known as niacin (a.k.a. nicotinic acid) and includes additional forms, nicotinamide and nicotinamide riboside. All forms increase blood nicotinamide adenine dinucleotide (NAD+) which is an essential molecule necessary for cellular metabolism, cellular defense and repair, and the production of cellular energy via ATP. Although niacin containing foods such as lean meat, fish, dairy and whole grains can support NAD+ synthesis, supplementing with NAD+ precursors provides a more impactful and significant increase.
NAD+ acts as a coenzyme for various mitochondrial enzymes and is critical for optimal cellular function. In short, NAD+ plays a fundamental role in our foundational health, which begins at the cellular level. It is linked to our body’s cellular defense and repair mechanisms, as well as mitochondrial health.
Scientists identified NAD+ over a century ago and it has been continuously studied. In 2004, Dr. Charles Brenner (Alfred E Mann Family Foundation Chair in Diabetes and Cancer Metabolism in the Department of Diabetes & Cancer Metabolism, with previous tenure and the Chief Science Advisor for ChromaDex) discovered the vitamin activity of nicotinamide riboside (NR), the third and most recently discovered form of vitamin B3. Subsequent research since his initial discovery has demonstrated that NR is the most efficient NAD+ precursor and can increase NAD+ blood levels by 40-50 percent.
The human body’s production or consumption (by cellular repair enzymes) of NAD+ can slow down considerably as people age. Human tissue studies demonstrate that NAD+ levels decrease by as much as 65 percent from ages 30 – 70. Metabolic stressors and certain lifestyle choices also play into the equation. For example, a high fat or high sugar diet, alcohol consumption, excess sun exposure, and overtraining can diminish the body’s supply of NAD+. Studies demonstrate that declines in NAD+ levels may be associated with several age-associated conditions.
NAD+ is a key factor in the understanding of how health can naturally decline as part of the aging process along with lifestyle choices. Time and repeated exposure to metabolic stressors can cause cellular energy production to decline, and with that comes a loss of vitality. Our cells’ ability to create energy and repair themselves is fundamental to health and well-being.
Niagen®, a patented form of NR and the sole active ingredient in Tru Niagen®, is one of the most efficient and studied modern NAD+ precursors.On average, taking 300mg per day of Tru Niagen® for eight weeks increases NAD+ levels in the body by 40-50 percent. NAD+ and its effects on the human body continue to be studied
What is nicotinamide riboside (NR)?
NR is a form of vitamin B3 that can be naturally found in milk but, as mentioned, these products are not an efficient way of increasing NAD+ levels in the body.
However, studies have shown that supplementation with NR effectively increases NAD+ levels.
Tru Niagen®, a patented and award-winning supplement clinically proven to increase NAD+levels was created by ChromaDex, a global bioscience company delivering science-based solutions that support energy metabolism and help encourage cellular health for consumers worldwide. Rob Fried, CEO of ChromaDex explains, “Tru Niagen® increases your levels of NAD+, which is critical to generating energy within the trillions of cells throughout your body. These levels inevitably decline over time and without NAD+, your cells cannot function properly and neither can you.”
NAD+ is especially important when the immune system is under attack and needs more energy to support the body’s regulation and recovery. To provide an extra boost of immune support, ChromaDex launched Tru Niagen® Immune, which is a first-of-its-kind combination of proven immune-boosting nutrition and NAD+ support (from our patented flagship supernutrient Niagen®) for the optimal maintenance and function of your cells. According to Mona Rosene, MS, RD, and ChromaDex Director of Scientific Affairs, “We wanted to develop a product to support immune health; therefore, we combined the proven immune-boosting nutrients vitamins C and D, and Zinc with a highly absorbable form of curcumin and Niagen®, our proprietary ingredient, which is essential for increasing NAD+.”
For optimal immune support and daily NAD+ replenishment, it’s recommended to take 300mg of Tru Niagen® 1-2 times a day in addition to 150mg of Tru Niagen® Immune. And on days when you’re feeling more depleted or not quite yourself, it might be a good idea to take additional Tru Niagen. Backed by over 20 published human clinical studies, over 250 research collaborations, and 200+ preclinical studies, Niagen® is scientifically proven to support healthspan with comprehensive cellular defense. Supplements can be an essential stepping stone toward improved health and wellbeing.
To order your supply of TruNiagen, visit https://www.truniagen.ca/